Comparison of a commercial multiplex real-time PCR to the cell cytotoxicity neutralization assay for diagnosis of clostridium difficile infections.

نویسندگان

  • Haihui Huang
  • Andrej Weintraub
  • Hong Fang
  • Carl Erik Nord
چکیده

A commercial multiplex real-time PCR assay (Cepheid Xpert C. difficile assay) for the diagnosis of Clostridium difficile infection was evaluated. The sensitivity and specificity of the Cepheid assay were 97.1% and 93.0% for fresh stools, using the cell cytotoxicity neutralization assay as the reference. Using PCR ribotyping as the reference for ribotype 027 strains, the corresponding figures were 100% and 98.1%, respectively.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 47 11  شماره 

صفحات  -

تاریخ انتشار 2009